I think it can be handy to set it on maximal 50 players, including youth. so ppeople have a chance to set a reserve team for friendlies and have optional some other players to replace them to main, if there is a red card or injury

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Have you seen teams with this many players?
Player rotation is also a tactic

you want have a second reserve team so it dont affect condition, so you need atleast 22 players

also you need some for replace if injury or red card, so letsay thats 4 people, thenb you come on 26 people

over 2 seasons new youth get promoted to main team, so there must be space to do that. if it count togeter 40, its fine

note that playing friendly costs coindition and you dont want use your main team for that

thats why i have several low skill average players, just for friendlies

other solution make friendlies not take condition, yeah then 17 players + youth is enough

I think 30 players is enough...energy drink and medical kit market will be dead if 1 team have 50 players... Injuries, players condition, red cards will not make effects... Just make rotation and we didn't need to buy goods from the market... Or you can make suggestion that 1 team can have 1000 players so you can always win :)